I really wouldn't call NAFTA "the most significant trade issue in world history." One of the odd realities of the bill, despite all the political organizing around it, is that it just didn't matter all that much. Trade agreements -- ranging from big ones like NAFTA to small ones like Peru -- attract a ton of political controversy because they're the only tangible political manifestations of globalization that anyone can actually fight for/against. But, in reality, what's driving trade is much more fundamental than free trade agreements. It's transportation, communication, and container technologies. it's the development of labor giants like China and India. It's the internet. It ain't NAFTA. But since no one is going to fight against the internet or shipping advances, all we can really do is have symbolic battles over so-called "free trade agreements."