As Mark Blumenthal notes, November polling from Democracy Corps had Rush Limbaugh's favorables at 23 and his unfavorables at 51. Now, no major Republican is doing well these days -- that's pretty close to John Boehner's numbers and only a little worse than Mitch McConnell.
But I like the idea of calling him out and making his corpulent mug the face of the GOP as much as possible. He's a generally unattractive figure who says outrageous things, and the more he's in the spotlight (see Missouri 2006), the more he'll hurt the Republican Party. You don't want him directing his dittohead zombie hordes from the shadows.