Ron Brownstein takes a look:
The stampede toward the GOP among blue-collar whites was powerful almost everywhere. In heartland states such as Arkansas, Ohio, Indiana, and even Illinois, Democrats were routed among college-educated whites, too, the exit polls found. But along the coasts -- in such states as Delaware, California, and Connecticut -- Democrats did a better job of holding college whites, especially women. That was critical to their Senate victories in those states. The exception to that coastal pattern was in Pennsylvania. Republican Pat Toomey attracted more of those suburban voters and, crucially, remained competitive in the Philadelphia suburbs (which two years ago gave Obama a crushing margin of nearly 200,000 votes); that helped power Toomey’s narrow victory over Democrat Joe Sestak. In Colorado, which shares many cultural characteristics with the coastal states, strong support among college-educated whites in metropolitan areas such as Denver and Boulder allowed Democratic Sen. Michael Bennet to remain in a tight race with Republican challenger Ken Buck despite Buck’s massive advantage among noncollege whites, especially in the state’s rural areas.
I would say that this makes comprehensive immigration reform super-dead for the next two years, since Democrats won't want to do anything that exacerbates the loss of working-class white voters. Still, Democrats can and should get the DREAM Act through the lame-duck. Given that Steve King of Iowa, who once called illegal immigration a "slow-motion holocaust" is now the likely head of the House Immigration Subcommittee, it's unlikely that anything not enforcement-focused is going to get through.